The epigenetic dimension of Alzheimer's disease: causal, consequence, or curiosity?

Abstract excerpt

Early-onset, familial Alzheimer's disease (AD) is rare and may be attributed to disease-causinq mutations. By contrast, late onset, sporadic (non-Mendelian) AD is far more prevalent and reflects the interaction of multiple genetic and environmental risk factors, together with the disruption of epigenetic mechanisms controlling gene expression. Accordingly, abnormal patterns of histone acetylation and methylation,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Birth, Development, and Health
• Share to Diet and metabolism studies
• Share to Epigenetics and DNA Methylation