Article

Whole-genome sequencing analysis of clozapine-induced myocarditis

2021-07-29

Abstract excerpt

<h4>ABSTRACT</h4> One of the concerns limiting the use of clozapine in schizophrenia treatment is the risk of rare but potentially fatal myocarditis. Our previous genome-wide association study and human leucocyte antigen analyses identified putative loci associated with clozapine-induced myocarditis. However, the contribution of DNA variation in cytochrome P450 genes, copy number variants and rare deleterious vari...

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Literature Corpus work: af8d940e-b4d1-5b4a-a0ef-b20f8c426cb3
DOI: 10.1101/2021.07.26.21261157

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