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Clozapine: An Updated Overview of Pharmacogenetic Biomarkers, Risks, and Safety—Particularities in the Context of COVID-19

2020-11-09

Abstract excerpt

<h4>Background: </h4> Clozapine (CLZ) use is precarious due to its neurological, cardiovascular, and hematological side effects; however, it is the gold standard in therapy-resistant schizophrenia (TRS) in adults and is underused. <h4>Objective:</h4> to examine the most recent CLZ data on (a) side effects concerning (b) recent pharmacological mechanisms, (c) therapy benefits, and (d) the particularities of the COV...

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Literature Corpus work
454fe115-cdcd-5859-bce9-7a4a5e5c23b1
DOI
10.20944/preprints202009.0724.v2
Open publication

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Clozapine: An Updated Overview of Pharmacogenetic Biomarkers, Risks, and Safety—Particularities in the Context of COVID-19DOI 10.20944/preprints202009.0724.v2
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