Article

Differential DNA Methylation and Gene Expression in Stem Cell-Derived Cardiomyocytes from Patients with and without a History of Clozapine-Induced Myocarditis.

2024-08-28

Abstract excerpt

<title>Abstract</title> <p>Clozapine is an effective antipsychotic medication for the management of treatment-resistant schizophrenia. However, the use of clozapine is limited due to severe and sometimes fatal adverse events, including cardiac inflammation (myocarditis). To date, studies of clozapine dosing and genetic studies have not identified robust risk markers. Our study aimed to identify potential epigenet...

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Literature Corpus work: 666b2106-c4bd-502d-9e53-72d785d5450b
DOI: 10.21203/rs.3.rs-4572577/v1

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