Article

Spatial proteomics identifies a novel CRTC-dependent viral sensing pathway that stimulates production of Interleukin-11

2024-04-07

Abstract excerpt

<h4>ABSTRACT</h4> Appropriate cellular recognition of viruses is essential for the generation of effective innate and adaptive antiviral immunity. Viral sensors and their signalling components thus provide a crucial first line of host defence. Many exhibit subcellular relocalisation upon activation, triggering expression of interferon and antiviral genes. To identify novel signalling factors we analysed protein r...

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Literature Corpus work: af477a15-cd8d-5d38-991f-8142930dfb49
DOI: 10.1101/2024.04.04.588067

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