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Article

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

2021-02-23

Abstract excerpt

Viral proteins localize within subcellular compartments to subvert host machinery and promote pathogenesis. To study SARS-CoV-2 biology, we generated an atlas of 2422 human proteins vicinal to 17 SARS-CoV-2 viral proteins using proximity proteomics. This identified viral proteins at specific intracellular locations, such as association of accessary proteins with intracellular membranes, and projected SARS-CoV-2 im...

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Identifiers and source

Literature Corpus work
8c552fc3-c879-59e2-a7ab-2a77ae075e63
DOI
10.1101/2021.02.23.432450
Open publication

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The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translationDOI 10.1101/2021.02.23.432450
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