Article

Local assembly of long reads enables phylogenomics of transposable elements in a polyploid cell line

2022-01-04

Abstract excerpt

<h4>ABSTRACT</h4> Animal cell lines cultured for extended periods often undergo extreme genome restructuring events, including polyploidy and segmental aneuploidy that can impede de novo whole-genome assembly (WGA). In Drosophila , many established cell lines also exhibit massive proliferation of transposable elements (TEs) relative to wild-type flies. To better understand the role of transposition during long-...

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Literature Corpus work: af431f96-d981-5610-b0de-be91f1db9bbf
DOI: 10.1101/2022.01.04.471818

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