Article

Rapid low-cost assembly of the <i>Drosophila melanogaster</i> reference genome using low-coverage, long-read sequencing

2018-02-18

Abstract excerpt

<h4>ABSTRACT</h4> Accurate and comprehensive characterization of genetic variation is essential for deciphering the genetic basis of diseases and other phenotypes. A vast amount of genetic variation stems from large-scale sequence changes arising from the duplication, deletion, inversion, and translocation of sequences. In the past 10 years, high-throughput short reads have greatly expanded our ability to assay s...

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Literature Corpus work: b4092a26-0d69-51cb-a325-a9b397d8b8ff
DOI: 10.1101/267401

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