Article

Drugs prescribed for Phelan-McDermid syndrome differentially impact sensory behaviors in shank3 zebrafish models.

2023-09-27

Abstract excerpt

<h4>Background: </h4> Altered sensory processing is a pervasive symptom in individuals with Autism Spectrum Disorders (ASD); people with Phelan McDermid syndrome (PMS), in particular, show reduced responses to sensory stimuli. PMS is caused by deletions of the terminal end of chromosome 22 or point mutations in Shank3 . People with PMS can present with an array of symptoms including ASD, epilepsy, gastrointestina...

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Literature Corpus work: af36489b-f64c-54d4-8c07-e529eb76cee4
DOI: 10.12688/f1000research.127830.2

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