Article

Androgen Receptor Signaling in Prostate Cancer and Therapeutic Strategies

2021-10-01

Abstract excerpt

Understanding of the molecular mechanisms of prostate cancer has led to development of therapeutic strategies targeting androgen receptor (AR). These androgen-receptor signaling inhibitors (ARSI) include androgen synthesis inhibitor- abiraterone and androgen receptor antagonists- enzalutamide, apalutamide, and darolutamide. Although these medications provide significant improvement in survival among men with prost...

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Literature Corpus work: af1f9feb-c297-5917-99d6-aead9898731d
DOI: 10.20944/preprints202110.0016.v1

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