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Novel hormone therapies for advanced prostate cancer: Understanding and countering drug resistance

22 Feb 2025

Abstract excerpt

Prostate cancer is the most prevalent malignant tumor among men, ranking first in incidence and second in mortality globally. Novel hormone therapies (NHT) targeting the androgen receptor (AR) pathway have become the standard of care for metastatic prostate cancer. This review offers a comprehensive overview of NHT, including abiraterone, enzalutamide, apalutamide, darolutamide, and rezvilutamide, which have...

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PMID: 41079787
DOI: 10.1016/j.jpha.2025.101232

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