Article

snPATHO-seq: unlocking the FFPE archives for single nucleus RNA profiling

2022-08-24

Abstract excerpt

FFPE (formalin-fixed, paraffin-embedded) tissue archives are the largest repository of clinically annotated human specimens. Despite numerous advances in technology, current methods for sequencing of FFPE-fixed single-cells are slow, labour intensive, insufficiently sensitive and have a low resolution, making it difficult to fully exploit their enormous research and clinical potential. Here we introduce single nuc...

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Identifiers and source

Literature Corpus work: 8bf3af91-635f-5e66-8878-c1b1f98ceba5
DOI: 10.1101/2022.08.23.505054

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