Article

Structure-Guided Design of Partial Agonists at an Opioid Receptor

2024-07-16

Abstract excerpt

<title>Abstract</title> <p>The persistence of chronic pain and continuing overdose deaths from pain-relieving opioids targeting µ opioid receptor (µOR) have fueled the need for reliable long-term analgesics which use different targets and mechanisms. The δ opioid receptor (δOR) is a potential alternative target for non-addictive analgesics to alleviate chronic pain, made more attractive by its lack of respiratory...

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Literature Corpus work: aea737f8-391e-56c8-89db-b5096cf03c36
DOI: 10.21203/rs.3.rs-4664764/v1

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