Article

Structural insights into the human P2X1 receptor and ligand interactions

2024-04-06

Abstract excerpt

The P2X1 receptor is a trimeric ligand-gated ion channel that plays a pivotal role in urogenital and immune functions. Consequently, it offers numerous potential indications for novel drug treatments. Unfortunately, the progress of drug discovery targeting the P2X1 receptor has been impeded by the absence of structural information. To gain deeper insights into the binding site of the P2X1 receptor, we employed cry...

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Literature Corpus work: e205a912-861d-56d9-9cc4-2cf6922e8749
DOI: 10.1101/2024.04.04.588192

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