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Hepatitis C Virus Remodels Lipid Droplets to Promote Mitochondrial Fatty Acid Accumulation and Metabolic Activation

2026-07-10

Abstract excerpt

<h4>ABSTRACT</h4> Hepatitis C virus (HCV) depends on host lipid metabolism and lipid droplets (LDs) for genome replication, assembly, and particle production, yet how LD structure and lipid utilization change over the course of infection remains incompletely understood. Here, we investigated the temporal remodeling of LD-associated metabolic pathways during HCV JFH-1 infection of human hepatoma Huh7 cells. HCV in...

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Literature Corpus work
2da7d8ca-b9fe-5b5c-b9bb-4f93028a6950
DOI
10.64898/2026.07.09.737644
Open publication

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Hepatitis C Virus Remodels Lipid Droplets to Promote Mitochondrial Fatty Acid Accumulation and Metabolic ActivationDOI 10.64898/2026.07.09.737644
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