Article

Convergent use of phosphatidic acid for Hepatitis C virus and SARS-CoV-2 replication organelle formation

2021-05-10

Abstract excerpt

Double membrane vesicles (DMVs) are used as replication organelles by phylogenetically and biologically distant pathogenic RNA viruses such as hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Viral DMVs are morphologically analogous to DMVs formed during autophagy, and although the proteins required for DMV formation are extensively studied, the lipids driving their biogene...

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Literature Corpus work: a3366b57-c557-502f-b5fc-5d027a715060
DOI: 10.1101/2021.05.10.443480

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