Article

A cancer-associated RNA polymerase III identity drives robust transcription and expression of SNAR-A noncoding RNA

2021-04-22

Abstract excerpt

<h4>ABSTRACT</h4> Dysregulation of the RNA polymerase III (Pol III) transcription program, which synthesizes tRNA and other classes of small noncoding RNA critical for cell growth and proliferation, is associated with cancer and human disease. Previous studies have identified two distinct Pol III isoforms defined by the incorporation of either subunit POLR3G (RPC7α) during early development, or POLR3GL (RPC7β) in...

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Literature Corpus work: ae96a33c-9f02-557f-b1a2-5b2fbda56a94
DOI: 10.1101/2021.04.21.440535

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