Article

Quantifying antibiotic susceptibility and inoculum effects using transient dynamics of <i>Pseudomonas aeruginosa</i>

2025-11-26

Abstract excerpt

Antibiotics are a cornerstone of modern medicine, targeting pathogen cells by disrupting essential cellular processes. However, standard antibiotic susceptibility metrics (e.g. MIC) and textbook models neglect transient dynamics and density-dependent effects, despite their ubiquity in nature. In clinical infections, where bacterial populations are the units we treat, this can increase the risk of under treatment....

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Literature Corpus work: 9b1e8649-27b1-5c5f-bb92-abd047d50f07
DOI: 10.1101/2025.11.26.690803

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