Article

Enhancer/gene relationships: need for more reliable genome-wide reference sets

2022-10-14

Abstract excerpt

Differences in cells’ functions arise from differential action of regulatory elements, in particular enhancers. Like promoters, enhancers are genomic regions bound by transcription factors (TF) that activate the expression of one or several genes by getting physically close to them in the 3D space of the nucleus. As there is increasing evidence that variants associated with common diseases are located in enhancers...

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Literature Corpus work: ae56af8b-ad03-54b2-ae0d-31de531426e0
DOI: 10.1101/2022.10.12.511908

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