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From Gene Networks to Therapeutics: A Causal Inference and Deep Learning Approach for Drug Discovery

2025-07-11

Abstract excerpt

<h4>Background: </h4> /Objectives: Drug discovery is a lengthy and expensive process, taking an average of 10 years and more than $2 billion from target discovery to drug approval. It is even more challenging in complex diseases due to the disease heterogeneity and limited knowledge about the underlying mechanisms. We present a novel computational framework that integrates network analysis, statistical mediation,...

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Literature Corpus work
ae3a3a24-1307-57e0-a8ae-3c211f4ef415
DOI
10.20944/preprints202507.1009.v1
Open publication

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From Gene Networks to Therapeutics: A Causal Inference and Deep Learning Approach for Drug DiscoveryDOI 10.20944/preprints202507.1009.v1
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