Article

Graphical Learning and Causal Inference for Drug Repurposing

2023-08-02

Abstract excerpt

Gene expression profiles that connect drug perturbations, disease gene expression signatures, and clinical data are important for discovering potential drug repurposing indications. However, the current approach to gene expression reversal has several limitations. First, most methods focus on validating the reversal expression of individual genes. Second, there is a lack of causal approaches for identifying drug r...

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Literature Corpus work: beac925d-aec8-5673-a1ce-9099659d2643
DOI: 10.1101/2023.07.29.23293346

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