Article

The MpsB protein contributes to both the toxicity and immune evasion capacity of <i>Staphylococcus aureus</i>

2021-06-30

Abstract excerpt

Understanding the role specific bacterial factors play in the development of severe disease in humans is critical if new approaches to tackle such infections are to be developed. In this study we focus on genes we have found to be associated with patient outcome following bacteraemia caused by the major human pathogen Staphylococcus aureus . By examining the contribution these genes make to the ability of the bac...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ae276caf-ac13-5206-9868-274998fa4d15
DOI: 10.1101/2021.06.30.450544

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The MpsB protein contributes to both the toxicity and immune evasion capacity of <i>Staphylococcus aureus</i>DOI 10.1101/2021.06.30.450544Read

The MpsB protein contributes to both the toxicity and immune evasion capacity of Staphylococcus aureus.Semantic proximity Read

Self-sensitisation of <i>Staphylococcus aureus</i> to the antimicrobial factors found in human bloodSemantic proximity Read

Expression of <i>mecA</i> reduces the daptomycin susceptibility of <i>Staphylococcus aureus</i>Semantic proximity Read

Extracellular proteases are key mediators of <scp> <i>S</i> </scp> <i>taphylococcus aureus</i> virulence via the global modulation of virulence‐determinant stabilitySemantic proximity Read

<i>Staphylococcus aureus</i> Resistance to Human Defensins and Evasion of Neutrophil Killing via the Novel Virulence Factor Mprf Is Based on Modification of Membrane Lipids with <scp>l</scp> -LysineSemantic proximity Read

The mcsB gene of the clpC operon is required for stress tolerance and virulence in Staphylococcus aureus.Semantic proximity Read

Metabolic reprogramming promotes <i>Staphylococcus aureus</i> serum resistance during bacteraemiaSemantic proximity Read

<i>Staphylococcus aureus</i>survival in human bloodSemantic proximity Read

A Functional Menadione Biosynthesis Pathway is Required for Capsule Production by <i>Staphylococcus aureus</i>Semantic proximity Read

A high-throughput cytotoxicity screening platform reveals <i>agr</i> -independent mutations in bacteraemia-associated <i>Staphylococcus aureus</i> that promote intracellular persistenceSemantic proximity Read

Metabolic reprogramming promotes Staphylococcus aureus serum resistance.Semantic proximity Read

A Small Membrane Stabilizing Protein Critical to the Pathogenicity of Staphylococcus aureus.Semantic proximity Read