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Extracellular proteases are key mediators of <scp> <i>S</i> </scp> <i>taphylococcus aureus</i> virulence via the global modulation of virulence‐determinant stability

11 Dec 2012

Abstract excerpt

Staphylococcus aureus is a highly virulent and successful pathogen that causes a diverse array of diseases. Recently, an increase of severe infections in healthy subjects has been observed, caused by community-associated methicillin-resistant S. aureus (CA-MRSA). The reason for enhanced CA-MRSA virulence is unclear; however, work suggests that it results from hypersecretion of agr-regulated toxins, including...

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PMID: 23233325
DOI: 10.1002/mbo3.55

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