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Article

The mcsB gene of the clpC operon is required for stress tolerance and virulence in Staphylococcus aureus.

Microbiology (Reading, England) - 1 Oct 2012

Wozniak Darren J, Tiwari Kiran B, Soufan Rami, Jayaswal Radheshyam K

Abstract excerpt

The clpC operon in Staphylococcus aureus comprises four genes, denoted ctsR, mcsA, mcsB and clpC. A mutation within the mcsB gene resulted in hypersensitivity to heavy metal stress, temperature stress, osmotic pressure stress and oxidative stress. This mutation also resulted in sensitivity to variations in pH and lowered expression of the clpC operon under adverse extracellular conditions, as determined by...

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Identifiers

PMID: 22902728
DOI: 10.1099/mic.0.060749-0
PMCID: PMC4083623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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