Article

Molecular Phenotyping of Patients with Sepsis and Kidney Injury and Differential Response to Fluid Resuscitation

2024-07-02

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold> Previous work has identified two AKI sub-phenotypes (SP1 and SP2) characterized by differences in inflammation and endothelial dysfunction. Here we identify these sub-phenotypes using biospecimens collected in the emergency department and test for differential response to restrictive versus liberal fluid strategy in sepsis-induced hypotension in the CLOVERS trial. <...

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Literature Corpus work: ae0e994a-27a8-59f6-825a-5f8f011de2b2
DOI: 10.21203/rs.3.rs-4523416/v1

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