Article
Derivation and Validation of Pediatric Sepsis-Associated Acute Kidney Injury Subphenotypes With Prognostic Relevance.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies - 1 Sept 2025
Stanski Natalja L, Zhang Bin, Ouyang Jiarong, Sanchez-Pinto L Nelson, Faustino E Vincent S, Rogerson Colin M, Hall Mark W, Weiss Scott L, Bennett Tellen D, Standage Stephen W, Goldstein Stuart L, Liu Kathleen D
Abstract excerpt
OBJECTIVES: Sepsis-associated acute kidney injury (SAKI) is a heterogeneous syndrome associated with poor outcomes. Subphenotypes of SAKI with prognostic and therapeutic relevance have been identified in adults, but not in children. We sought to identify reproducible and clinically relevant pediatric SAKI (pSAKI) subphenotypes using readily available clinical and laboratory data. DESIGN: Secondary analysis of a...
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