Article

The bacterial metabolite, lithocholic acid, has antineoplastic effects in pancreatic adenocarcinoma

2024-04-30

Abstract excerpt

<title>Abstract</title> <p>Lithocholic acid (LCA) is a secondary bile acid. LCA enters the circulation after bacterial synthesis in the gastrointestinal tract, reaches distantly located cancer cells, and influences their behavior. LCA was considered carcinogenic, but recent studies demonstrated that LCA has antitumor effects. We assessed the possible role of LCA in pancreatic adenocarcinoma. At the serum referenc...

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Literature Corpus work: adeb91d4-c1db-5209-977a-bd49b08b2ecd
DOI: 10.21203/rs.3.rs-3330981/v1

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