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Paclitaxel chemotherapy disrupts microbiota-enterohepatic bile acid metabolism in mice

1 Oct 2024

Abstract excerpt

Balanced interactions between the enteric microbiota and enterohepatic organs are essential to bile acid homeostasis, and thus normal gastrointestinal function. Disruption of these interactions by cancer treatment instigates bile acid malabsorption, leading to treatment delays, malnutrition, and decreased quality of life. However, the nature of chemotherapy-induced bile acid malabsorption remains poorly...

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Drug Transport and Resistance Mechanisms
Gut microbiota and health
Pharmacological Effects and Toxicity Studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39353099
DOI: 10.1080/19490976.2024.2410475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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