Article

Dystrophin-deficiency stiffens skeletal muscle and impairs elasticity: an <i>in vivo</i> rheological examination

2025-05-28

Abstract excerpt

Loss of dystrophin alters the biomechanical properties of skeletal muscle, including stiffness. Stiffness is typically assessed passively in excised muscle, but here we present the development of an in vivo rheological method to assess the mechanical properties of the tibialis anterior muscle in anaesthetised wild-type (WT; dystrophin-positive) and mdx (dystrophin-deficient) mice using a custom-designed apparatu...

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Literature Corpus work: add0c4aa-50aa-55c7-ad29-e0617a962977
DOI: 10.1101/2025.05.25.655634

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