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Article

Bone is functionally impaired in dystrophic mice but less so than skeletal muscle.

Neuromuscular disorders : NMD - 1 Mar 2011

Novotny Susan A, Warren Gordon L, Lin Angela S, Guldberg Robert E, Baltgalvis Kristen A, Lowe Dawn A

Abstract excerpt

The primary purpose of this study was to determine if tibial bone strength is compromised in dystrophic mice and if so, what geometric and material properties contribute. Results of three-point bending tests showed that tibia of mdx and dko (dystrophin- and utrophin-deficient) mice had up to 50% lower strength and stiffness compared to wild-type mice. Micro-computed tomography indicated that dystrophic tibia had...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred mdx

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Share to Muscular Dystrophy, Duchenne

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Source

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Identifiers

PMID: 21256750
DOI: 10.1016/j.nmd.2010.12.002
PMCID: PMC3046261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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