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Familial Whole Exome Sequencing Study of 30 Families With Early-Onset High Myopia.

Investigative ophthalmology & visual science - 1 May 2023

Yang Entuan, Yu Jifeng, Liu Xue, Chu Huihui, Li Li

Abstract excerpt

Purpose: This study was conducted to investigate potential candidate pathogenic genes in early-onset high myopia (eoHM) in families with eoHM. Methods: Whole-exome sequencing was performed on probands with eoHM to identify potential pathogenic genes. Sanger sequencing was used to verify the identified gene mutations causing eoHM in first-degree relatives of the proband. The identified mutations were screened out...

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Identifiers

PMID: 37191617
DOI: 10.1167/iovs.64.5.10
PMCID: PMC10198284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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