Article

Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease

2022-09-29

Abstract excerpt

Genome-wide association studies (GWAS) of hair and skin disease have identified many genetic variants associated with disease phenotypes, but identifying causal variants and interpreting their function requires deciphering gene-regulatory networks in disease-relevant cell types. To this end, we generated matched scRNA- and scATAC-seq profiles of human scalp biopsies, identifying diverse cell types of the hair foll...

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Literature Corpus work: ada275ee-65d1-5295-9d00-e5eec3438bcb
DOI: 10.1101/2022.09.28.509620

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