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Article

Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles.

BMC dermatology - 10 Nov 2020

Herrera-Rivero Marisol, Hochfeld Lara M, Sivalingam Sugirthan, Nöthen Markus M, Heilmann-Heimbach Stefanie

Abstract excerpt

BACKGROUND: The association of molecular phenotypes, such as gene transcript levels, with human common genetic variation can help to improve our understanding of interindividual variability of tissue-specific gene regulation and its implications for disease. METHODS: With the aim to capture the spectrum of biological processes affected by regulatory common genetic variants (minor allele frequency ≥ 1%) in healthy...

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PMID: 33167971
DOI: 10.1186/s12895-020-00113-y
PMCID: PMC7653834

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