Article

Prenatal Cannabidiol and THC Exposure Induce Sex-Specific Executive Dysfunction via Divergent Pathological Rewiring of the Adult Medial Prefrontal Cortex

2026-04-27

Abstract excerpt

<title>Abstract</title> <p>Prenatal cannabidiol (CBD) consumption is rapidly increasing, driven by a perception of safety relative to delta9-tetrahydrocannabinol (THC). However, the long-term neurodevelopmental risks of gestational CBD remain largely uncharacterized. Using a sex-disaggregated framework, we investigated adult (P100–140) mouse offspring following in utero exposure (GD5–18; 3 mg/kg) to THC or CBD. E...

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Literature Corpus work: e37d28b3-881b-52f3-9723-aeb332668b51
DOI: 10.21203/rs.3.rs-9428628/v1

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