Article

Specification and epigenetic resetting of the pig germline exhibit conservation with the human lineage

2020-08-07

Abstract excerpt

<h4>Summary</h4> Investigations on the human germline and programming are challenging due to limited access to embryonic material. However, the pig as a model may provide insight on transcriptional network and epigenetic reprogramming applicable to both species. Here we show that during the pre- and early migratory stages pig primordial germ cells (PGCs) initiate large-scale epigenetic reprogramming, including DN...

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Literature Corpus work: ad73b8c8-fc4a-56d8-bd16-af614bba6dd7
DOI: 10.1101/2020.08.07.241075

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