Article
Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model.
BMC genomics - 5 Oct 2015
Schachtschneider Kyle M, Madsen Ole, Park Chankyu, Rund Laurie A, Groenen Martien A M, Schook Lawrence B
Abstract excerpt
BACKGROUND: Pigs (Sus scrofa) provide relevant biomedical models to dissect complex diseases due to their anatomical, genetic, and physiological similarities with humans. Aberrant DNA methylation has been linked to many of these diseases and is associated with gene expression; however, the functional similarities and differences between porcine and human DNA methylation patterns are largely unknown. METHODS: DNA...
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