Article

Investigating inflammatory pathways as therapeutic targets and biomarkers using functional imaging and pharmacological interventions in epilepsy models

2018-01-01

Abstract excerpt

Epilepsy is a neurological disorder that is characterised by spontaneous seizures. After various epileptogenic injuries, astrocytes become dysfunctional and experimental evidence indicates that these cells contribute to seizure mechanisms. The generation of inflammatory molecules in astrocytes appears to play a key pathogenic role in seizures. However, astrocytes may also contribute to repair the hyperexcitable ne...

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Literature Corpus work: ad59c959-b560-5ac8-95df-96704f5e370d
DOI: 10.21954/ou.ro.0000e1ad

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