Severe Acute Respiratory Syndrome Coronavirus Pathogenesis, Disease and Vaccines

Abstract excerpt

BACKGROUND: A novel coronavirus has recently been identified as the cause of severe acute respiratory syndrome (SARS-CoV). The ability of this family of positive strand RNA viruses to move between species and cause severe disease in humans, with the potential for pandemic spread, has been confirmed. METHODS: An understanding of the disease and its pathogenesis and the genetics of coronavirus infections, as well...

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