Article

Amygdala TDP-43 pathology is associated with behavioural dysfunction and ferritin accumulation in amyotrophic lateral sclerosis

2024-06-01

Abstract excerpt

<h4>Background</h4> Cognitive and behavioural symptoms associated with amyotrophic lateral sclerosis and frontotemporal spectrum disorders (ALSFTSD) are thought to be driven, at least in part, by the pathological accumulation of TDP-43. <h4>Methods</h4> Here we examine post-mortem tissue from six brain regions associated with cognitive and behavioural symptoms in a cohort of 30 people with sporadic ALS (sALS),...

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Literature Corpus work: ace0b2aa-7795-50ef-87c8-2d03c2e211ed
DOI: 10.1101/2024.06.01.596819

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