Article

Synergistic Material-Topography Combinations to Achieve Immunomodulatory Osteogenic Biomaterials

2020-05-02

Abstract excerpt

Human mesenchymal stem cells (hMSCs) are widely represented in ongoing regenerative medicine clinical trials due to their ease of autologous implantation. In bone regeneration, crosstalk between macrophages and hMSCs is critical with macrophages playing a key role in the recruitment and differentiation of hMSCs. However, engineered biomaterials able to both direct hMSC fate and modulate macrophage phenotype have n...

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Literature Corpus work: acd91485-7829-5020-932b-263c323bb22b
DOI: 10.1101/2020.04.29.067421

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