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Biomimetic Surface Patterning Promotes Mesenchymal Stem Cell Differentiation

17 Dec 2015

Abstract excerpt

Both chemical and mechanical stimuli can dramatically influence cell behavior. By optimizing the signals cells experience, it may be possible to control the behavior of therapeutic cell populations. In this work, biomimetic geometries of adhesive ligands, which recapitulate the morphology of mature cells, are used to direct human mesenchymal stem cell (HMSC) differentiation toward a desired lineage. Specifically,...

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PMID: 26674708
DOI: 10.1021/acsami.5b08978

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