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An Anti-Glypican-2 Monoclonal Antibody, G<sub>2</sub>Mab-7, for Flow Cytometry, Western Blotting, and Immunohistochemistry

2026-02-03

Abstract excerpt

Glypican-2 (GPC2) is a heparan sulfate proteoglycan that plays essential roles in enhancing re-ceptor signaling by recruiting heparan sulfate-binding ligands. Overexpression of GPC2 is ob-served in pediatric cancers, including neuroblastoma and medulloblastoma, where it supports oncogenic signaling and tumor progression. High-affinity GPC2 binders have been developed as effective immunotherapies targeting tumors w...

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Literature Corpus work
c744fef5-faad-5b6f-92d0-506bd663e452
DOI
10.20944/preprints202602.0197.v1
Open publication

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An Anti-Glypican-2 Monoclonal Antibody, G<sub>2</sub>Mab-7, for Flow Cytometry, Western Blotting, and ImmunohistochemistryDOI 10.20944/preprints202602.0197.v1
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