Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KCNG4 Genetic Variant Linked to Migraine Prevents Expression of KCNB1.

International journal of molecular sciences - 17 Aug 2024

Lacroix Gabriel, Bhat Shreyas, Shafia Zerghona, Blunck Rikard

Abstract excerpt

Migraines are a common type of headache affecting around 15% of the population. The signalling pathways leading to migraines have not been fully understood, but neuronal voltage-gated ion channels, such as KCNG4, have been linked to this pathology. KCNG4 (Kv6.4) is a silent member of the superfamily of voltage-gated potassium (Kv) channels, which expresses in heterotetramers with members of the KCNB (Kv2) family....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to HEK293 Cells
Share to Migraine Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Potassium Channels, Voltage-Gated

Source

Open in PubMed Open full text

Identifiers

PMID: 39201645
DOI: 10.3390/ijms25168960
PMCID: PMC11354983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KCNG4 Genetic Variant Linked to Migraine Prevents Expression of KCNB1.PMID 39201645Read ↗

Functional properties of a disease mutation for migraine in Kv2.1/6.4 channelsSemantic proximity Read ↗

Functional properties of a disease mutation for migraine in Kv2.1/6.4 channels.Semantic proximity Read ↗

A pain-reducing Kv6.4 variant spares other Kv6 channels, offering a target for uterine painSemantic proximity Read ↗

Effects of familial hemiplegic migraine type 1 mutation T666M on voltage-gated calcium channel activities in trigeminal ganglion neurons.Semantic proximity Read ↗

Genetics of Migraine: Insights into the Molecular Basis of Migraine Disorders.Semantic proximity Read ↗

Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura.Semantic proximity Read ↗

Human labour pain is influenced by the voltage-gated potassium channel K <sub>V</sub> 6.4 subunitSemantic proximity Read ↗

Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel KV6.4 Subunit.Semantic proximity Read ↗

Current Update on Categorization of Migraine Subtypes on the Basis of Genetic Variation: a Systematic Review.Semantic proximity Read ↗

[Genetics of migraine].Semantic proximity Read ↗

Migraine: a complex genetic disorder.Semantic proximity Read ↗

Migraine: Genetic Variants and Clinical Phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.