Article

Induced pluripotent stem cell-derived primary proprioceptive neurons as Friedreich ataxia cell model

2019-11-06

Abstract excerpt

Human induced pluripotent stem cells (iPSCs) are used to generate models of human diseases that recapitulate the pathogenic process as it occurs in affected cells. Many differentiated cell types can currently be obtained from iPSCs, but no validated protocol is yet available to specifically generate primary proprioceptive neurons. Proprioceptors are affected in a number of genetic and acquired diseases, including...

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Literature Corpus work: ac43d924-8919-504f-ac80-3b3ab93d2c27
DOI: 10.1101/829358

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