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PCR-Based Techniques for Leprosy Diagnosis: From the Laboratory to the Clinic

10 Apr 2014

Abstract excerpt

In leprosy, classic diagnostic tools based on bacillary counts and histopathology have been facing hurdles, especially in distinguishing latent infection from active disease and diagnosing paucibacillary clinical forms. Serological tests and IFN-gamma releasing assays (IGRA) that employ humoral and cellular immune parameters, respectively, are also being used, but recent results indicate that quantitative PCR...

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PMID: 24722358
DOI: 10.1371/journal.pntd.0002655

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