Article
Polymorphisms in cytokine genes define subpopulations of HIV-1 patients who experienced immune restoration diseases.
AIDS (London, England) - 18 Oct 2002
Price Patricia, Morahan Grant, Huang Dexing, Stone Emma, Cheong Karey Y M, Castley Alison, Rodgers Marina, McIntyre Meredith Q, Abraham Lawrence J, French Martyn A
Abstract excerpt
OBJECTIVE: To further elucidate the immunopathogenesis of immune restoration diseases (IRD) in HIV patients responding to antiretroviral therapy and determine whether IRD associated with different opportunistic pathogens involve distinct immunopathological mechanisms. DESIGN: DNA samples from patients with a range of IRD were typed for polymorphic loci in genes encoding immune-mediators. METHODS: PCR-restriction...
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