Article

Carbonara: A Rapid Method for SAXS-Based Refinement of Protein Structures

2025-05-02

Abstract excerpt

<title>Abstract</title> <p>Generative machine learning models for protein structure prediction are primarily trained on X-ray crystallography data, which captures proteins in crystal lattices that can deviate significantly from their native solution conformations. Biological small angle X-ray scattering (bioSAXS) offers valuable solution-state insights, but creating atomic models that rationalise this data remain...

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Literature Corpus work: abe5a91a-cb7f-50de-b55d-3cc62b69381e
DOI: 10.21203/rs.3.rs-6447099/v1

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