Article

Non-Genetic Reprogramming of Monocytes via Microparticle Phagocytosis for Sustained Modulation of Macrophage Phenotype

2019-06-18

Abstract excerpt

<h4>ABSTRACT</h4> Monocyte-derived macrophages orchestrate tissue regeneration by homing to sites of injury, phagocytosing pathological debris, and stimulating other cell types to repair the tissue. Accordingly, monocytes have been investigated as a translational and potent source for cell therapy, but their utility has been hampered by their rapid acquisition of a pro-inflammatory phenotype in response to the in...

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Literature Corpus work: aba87e45-4ecd-5328-94e6-7c38bf1bd304
DOI: 10.1101/674598

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