Article
Macrophage-specific nanotechnology-driven CD163 overexpression in human macrophages results in an M2 phenotype under inflammatory conditions.
Immunobiology - 1 Aug 2017
Alvarado-Vazquez Perla Abigail, Bernal Laura, Paige Candler A, Grosick Rachel L, Moracho Vilrriales Carolina, Ferreira David Wilson, Ulecia-Morón Cristina, Romero-Sandoval E Alfonso
Abstract excerpt
M1 macrophages release proinflammatory factors during inflammation. They transit to an M2 phenotype and release anti-inflammatory factors to resolve inflammation. An imbalance in the transition from M1 to M2 phenotype in macrophages contributes to the development of persistent inflammation. CD163, a member of the scavenger receptor cysteine-rich family, is an M2 macrophage marker. The functional role of CD163...
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