Article

Telomeric Repeat-Containing RNA Increases in Aged Human Cells

2024-11-15

Abstract excerpt

Telomeric repeat-containing RNA (TERRA), transcribed from subtelomeric regions towards telomeric ends, poses challenges in deciphering its complete sequences. Utilizing TERRA-capture RNA-seq and Oxford Nanopore direct RNA sequencing to acquire full-length TERRA, we annotate TERRA transcription regions in the human T2T-CHM13 reference genome. TERRA transcripts encompass hundreds to over a thousand nucleotides of te...

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Literature Corpus work: ab669ece-f9fe-5701-8c35-dd3174c1be2a
DOI: 10.1101/2024.11.14.623513

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